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Old 11-27-2008, 06:05 PM
pabb pabb is offline
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Join Date: Sep 2006
Posts: 779
15 yr Member
pabb pabb is offline
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Join Date: Sep 2006
Posts: 779
15 yr Member
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Quote:
Originally Posted by MelodyL View Post
"Curcumin is a natural phenolic component of yellow curry spice, which is used in some cultures for the treatment of diseases associated with oxidative stress and
inflammation. Curcumin has been reported to be capable of preventing the death of neurons in animal models of neurodegenerative disorders, but its possible effects
on developmental and adult neuroplasticity are unknown. In the present study, we investigated the effects of curcumin on mouse multi-potent neural progenitor cells (NPC) and adult hippocampal neurogenesis. Curcumin exerted biphasic effects
on cultured NPC; low concentrations stimulated cell proliferation, whereas high concentrations were cytotoxic. Curcumin activated extracellular signal-regulated
kinases (ERKs) and p38 kinases, cellular signal transduction pathways known to be involved in the regulation of neuronal plasticity and stress responses. Inhibitors of ERKs and p38 kinases effectively blocked the mitogenic effect of
curcumin in NPC. Administration of curcumin to adult mice resulted in a significant increase in the number of newly generated cells in the dentate gyrus of hippocampus, indicating that curcumin enhances adult hippocampal neurogenesis. Our findings suggest that curcumin can stimulate developmental and adult hippocampal neurogenesis, and a biological activity that may enhance neural plasticity and repair."
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Mrs. D. The only part of the above paragraph that I understood was where it mentioned hippocampal. (This refers to short term memory right??) Or am I dead wrong here?

If this curcumin helps THAT, I'll go out and buy some tomorrow.

But do me a favor. Talk to me like I'm brain dead and translate the rest.

For example.

What this means is that if you use curcumin in your diet, you'll have a better memory, live longer, etc.

Because I couldn't understand ANY of it. I feel like a dodo bird among swans.

But hey, I'M LEARNING ALL ABOUT SPROUTS!!!

lol
Melody
well, melllllll, i think you found THE most compex listing on pumed.....i think what it is saying is it helps with repair..and increases plasticity which is ..hmm the ability of the cells/brain to adapt....it does cross the blood brain barrier... many things dont, it seems to help with insulin resistance and helps with mood,via two pathways apparently....the MAO and possibly reducing intracranial inflammation.....i am not sure of how it helps with the insulin resistance....and, no not cumin.....turmeric is the spice.....mccormack does put it out.....i would be surprised if the market doesnt carry it....ask for the person who does the ordering for that dept......good luck
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