I can't imagine how you could have heard only "not good" things about Naltrexone, so I'm wondering if perhaps you have LD Naltrexone confused with Novantrone. Novantrone is a somewhat risky chemo drug that is approved for advanced or particularly aggressive MS, whereas LDN is very low dosage of opioid antagonist, used off-label for all categories of MS.

I decided to go on LDN about 4 yrs ago, and it took me 6 months to convince my doctor. I heard about it through a friend, who's 13 yr old son had very aggressive MS. She had tried him on all the CRABs before she finally resorted to LDN ... which she had heard about on the internet. He quickly stabilized, and was able to get back to school. He had been on about 2 yrs at that point.

I didn't go on LDN for symptom improvement, and really never expected any either. I had been on a downhill slide for several years, especially the last two though, so I just wanted to try something to hopefully reduce relapses and slow the disease process. Within a week though, the relentless spasticity pain I'd been living with for that two years was gone, as was my claw hand (which had been getting worse for 5 yrs), improved bladder/bowel control, cogfog, walking/balance, etc.

Historically, most doctors and neuro's wouldn't "suggest" LDN to their patients because it is not a mainstream disease modifying treatment (DMT). Back when I was first looking for it, not many doctors had experience with it for MS, so they were reluctant to rx. Now-a-days though, almost every doctor has heard of the use of it for MS, many will rx, and some even recommend it (with or without clinical trials proving it's effectiveness).

Cherie