Magnate
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Join Date: Aug 2006
Location: Queens, NY
Posts: 2,857
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Magnate
Join Date: Aug 2006
Location: Queens, NY
Posts: 2,857
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Not everyone with sensory peripheral neuropathy--
--will experience ataxia; it often depends on just what fibers are affected (and if there is any central nervous system component to the situation as well).
As the Wikipedia article indicates, ataxia can stem both from brain/cerebellular dysunction, and from peripheral sensory dysfunction--it can often be hard to tell apart centrally-based symptoms from peripherally-based ones (as it is with many neural symtpoms).
I do think an underappreciated origin for certain ataxic people is autoimmune attack--such a mechanism is at work in lupus-associated ataxia and in gluten ataxia (in this latter the attack is on the Purkinje cells of the cerebellum). Anyone whose neuropathy has an autoimmune component (which probably includes a lot of idiopathic people) should be aware of this possibility.
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