I was started on Requip and titrated up to 12 mgs. before starting Sinemet. Requip did help with bradykinesis and rigidity but Sinemet was the one that finally gave me some relief from dystonia. The cramping and pain subsided only to reappear at end of dose and throughout the night. Dystonia is most uncomfortable and has been with me since before dxs. Fortunately I don't have a tremor. Trying to look on the bright side if there is one when you have P.D.