Originally Posted by Ronhutton

Hi Olsen,
I did a lot of research on this route some years ago, looking to get pure levodopa directly into the brain, via a nasal spray (ie with no carbidopa), as a means to get immediate activation with a minimum of side effects. I corresponded with a pharma company and encouraged them to research the route, but they gave up after a while. The nasal route to drug delivery has been investigated for a number of other illnesses.
I also looked into getting other substances into the brain directly such as glutathione. See this post.
Ron
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Quote:
Originally Posted by smithclayriley
This many posts is embarrassing but I had to do it


http://www.discoveritonline.biz/alternative.html

Smithclayriley,
Interesting link, many thanks. I was particularly interested in the glutathione (GSH) nasal spray. Glutathione is a very good antioxidant, which has been pioneered by Dr Perlmutter. However, it breaks down in the body when taken orally, and the usual way of taking it is by injection. So the reference to taking it via a nasal spray is very interesting. The nasal passage by-passes the BBB, and rapidly gets direct to the brain.
As an aside, glutathione protects the blood-brain barrier,
"Our studies showed that cerebral GSH plays an important role in maintaining the functional BBB integrity."
http://www.ingentaconnect.com/conten...e?format=print
The only problem is sourcing it. On your link, it says,
"I have recently heard from Sugit (my Dutch friend in Japan) that a glutathione nasal spray has been amazingly useful for him - more so than just about anything else he has tried. The only place he knows of to get it is a compounding pharmacy in the US - http://www.keynutritionrx.com/ (and you need a Doctor's prescription)"
Ron
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Diagnosed Nov 1991.
Born 1936

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