Holly - Thanks for posting that. Very well said. I too don't taper after IVSM and it does take me a few weeks to notice any improvement. However, most of my flares have been due to spinal lesions and it takes a good 4-6 weeks to start feeling any better. Additionally, my neuro doesn't give IVSM for spinal lesion flares as he feels the IVSM doesn't help. I just have to wait them out.