Sally,

A couple of years ago I attended a mini fatigue seminar here in London Canada sponsored by the local MS Society. The guest neurologist stated that recent discoveries at the time indicated that MS fatigue may be caused by a lack of proper chemical activity within the cells of the brain. I never got a chance to ask the doc to elaborate on that because she had to leave and catch a flight back home.

My wife Marg, since progressing to SPMS, always had a terrible fatigue problem. She would wake up after a night's sleep, walk 30 feet to the kitchen using her walker at the time, and be exhausted! In June of 2000, she started to use Prokarin and one of the first, most dramatic changes in her condition back then was a huge reduction in fatigue. Six and half years later and still using Prokarin, she has been able to control this fatigue to a great extent.

Prokarin helps cells in the brain operate properly. Perhaps MS fatigue is indeed caused by some kind of chemical imbalance and has little to do with demylinated nerves. Just one more mystery about the disease.

Harry