Hi Rick,
I think we are going off at tangents, discussing everything but the original suggestion. Why not if we can store dopamine, get it into the brain easily, by the nasal route???? It is fast and avoids side effects.
I shouldn't like to spend time trying to coincide a malfunction in the BBB with trying to rush past a blob of levodopa!! That is even if sugar opens the BBB, and if it did, toxins can also rush in. We need ways of tightening the BBB.
In any case, levodopa easily passes the BBB anyway, so why attempt to do it the hardest way possible. Just keep taking your sinemet.
Also, you are going back to oral delivery, with all its side effect problems.
These suggestons are a different thread, why not debate the pros and cons of this idea.
Ron