I don't use a pill box, but I do have a system. I keep all my meds in the kitchen. I have a dated jounal/book, that I write down the name of the pills and time as I take them. Because I could never remeber if I took a med, I was always second guessing myself.Here's my method. I've used it for about 3 years.

1. take pill out of bottle
2. write name in in book with time
3. put pill in little dish by book
4. by now I have 4-5 meds in dish.
5. take meds
6. If dish is empty I took my meds. (brain is gone).

Also good if you take prn meds, so you can look on book to see what you took and what time. It's really easy when you get the system down, and a good refernce for prn meds!!