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Old 11-26-2006, 07:06 AM
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mrsD mrsD is offline
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Join Date: Aug 2006
Location: Great Lakes
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15 yr Member
mrsD mrsD is offline
Wisest Elder Ever
mrsD's Avatar
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Default Dear Twofish...

I wonder why you are on Inderal? Inderal (propranolol) is not used much any
longer, in favor of the newer betablockers.
Quote:
:Am J Psychiatry 1982; 139:1187-1188
Copyright © 1982 by American Psychiatric Association

REGULAR ARTICLES
Substitution of atenolol for propranolol in a case of propranolol- related depression

GN McNeil, PK Shaw and DS Dock

The authors describe a 62-year-old woman with symptoms of major depression presumed to be secondary to propranolol use. The patient responded poorly to imipramine; however, her symptoms cleared rapidly when atenolol was substituted for propranolol.
and regarding memory:
Quote:
Memory-altering drug research is currently focused on propranolol, one of several so-called beta blockers widely used to reduce blood pressure, treat abnormal heart rhythms and prevent migraines. The brand name for propranolol is Inderal. Other beta blocker brand names are Inderide, Innopran XL, Betachron E-R, Kerlone, Lopressor, Tenormin, Toprol XL, Visken and Zebeta.

Beta blockers work by "blocking" the stimulative influence of stress hormones – specifically adrenaline – upon the body, relaxing blood vessels and slowing nerve impulses inside the heart.

Experiments indicate propranolol also blocks the effect of adrenaline upon areas of the brain involved in memory formation, including the amygdala. It seems to disconnect emotion from memory.
from http://www.cognitiveliberty.org/neur..._drugs_sd.html

Also Depakote depletes l-carnitine. I would suggest you have your physician test your carnitine levels. A supplement of this if low may help you dramatically. Carnitine is necessary for proper mitochondrial functions...mitochondria are the energy producing factories in your cells.
There is a link to secondary carnitine deficiency and Depakote in the thread here by Ellie about Foot pain. You may be able to improve your functions with a supplement and a conversation with the doctor as to the necessity of Inderal and perhaps a medication switch. Never hesitate to complain of loss of quality of life while on seizure meds. Most of them cause significant side effects, and doctors are aware of this and will try to pick ones that work better for you.
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