Hi hun, Reed had the clonidine patch for a couple of days, but it caused his blood pressure to drop really bad so he was take off it. The short time he had it, it was hard to tell if it helped with pain because he was so drowsy from the low BP. his doc prescribed it one patch on his rsd foot, for 3 days ( I think) then add another. We didn't get that far. It works well from some people, just not Reed.