hi jess
I'm the new kid on the block but have had pn for 30+ yrs.. at one time I was taking 4000mg neurontin and just today my pcp moved me up to 400mg lyrica(from 300mg) the lyrica took a long time (45+days) to kick in but am very satisfied with the results and am glad I stuck it out and waited for it to begin working. weight gain was insignificant when compared to pain reduction. a semi-complete list of my meds is on the thread "new and ignerent" although today I also stopped the percocet and am trying avinza 30mg and also tylenol #4 (hate the tylenol, is to hard on my liver) as I am building a tolerance to the opiates. hope you find what works for you