After 25 yearsof migraines and a three page double column list of medicatiions I have tried both off and on label, my doctor finally took me back for Fiorinal, but he told me to take it WITH Imitrex!!! I had used both Fiorinal and Fioricet back in the 80's ish I think. I can't take anything with Tylenol since it is my worst external migraine trigger, so I stick to the Fiorinal.

When I take the Fiorinal and Imitrex, I usually get drowsy which is a side effect I don't even get from medicines designed to make you drowsy. 99% of the time I have moderate relief and well over 50% of the time, that med combo actual completely knocks out a migraine that has me vomiting and unable to tolerate even the sound of the refrigerator in the front room.

Definitely try the Fioricet and if your doctor ok's it, you might want to take it with whatever triptan works best for you.

Good luck,
Suzanne