I started at 3.0mg and the side effects were not really bad. I had nausea (until I started downing a glass of water with it, which you should do when you are starting out anyway). I also had a mild headache for a few weeks, not much sleep for several days (but I still felt good during the day), and a "buzz" for about 30 min after I took it. I think that was it.

Cherie,

I have had past drugs that didn't allow me sleep and made me manic. I'm now afraid of LDN for that reason and my bp and having two past mini-strokes because of my bp which started after the MS dx. I was put on bp medication at age 32.

BTW, I was told by my psychiatrist that people with MS are twice as likely to become bipolar than the general population.

Thanks for the information and for caring.

Stac