Quote:
Originally Posted by komokazi
Your PML stats are wrong. Check page 14 of this link:
//library.corporate-ir.net/library/14/148/148682/items/278364/Q4-07%20Earnings%20Slides.pdf
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As per your link:
Quote:
Safety as of December 2007
Mid December: TYSABRI exposure in the clinical trial and post-marketing settings
• ~30,900 patients ever exposed
• ~6,300 patients exposed for at least one year
Late December: No new cases of PML since re-launch in US and launch Internationally in July 2006.
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Do you see where they are referring to “
ever exposed”, “
in the clinical trial and post-marketing settings”, and “
Cumulative total patient exposure”? They are talking about ALL persons who’ve EVER tried Tysabri, including those from the clinical trials.
As per my link (below), as at June/08 the numbers were:
Quote:
“As of the end of June 2008, more than 31,800 patients were receiving natalizumab. Specific to the TOUCH Prescribing Program, 21,099 patients were enrolled and had received natalizumab through the TOUCH program at the end of June 2008."
"Patients enrolled in the TOUCH program have received a median of 8 infusions (range: 1-28), with 7,538 patients receiving natalizumab for at least 1 year and 3,304 patients receiving the agent for at least 18 months.
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The following paragraph refers to the "cummulative" numbers,
just as your link did.
Quote:
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"As of June 2008, approximately 43,300 patients have been exposed to natalizumab in clinical study and postmarketing settings combined, with approximately 13,900 patients with at least 1 year of natalizumab exposure and approximately 6,600 patients with at least 18 months' exposure."
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The 3,304 patients are those that were enrolled in TOUCH (in June/08), and had recieved Tysabri for 18+ months. The 6600 number is how many have taken it for that long in
total, cumulatively, including all the trials.
Therefore, the 6600 number (which is now 9500, or at least last we heard in Dec), includes the 3000 (or there-abouts) from the trials, just as the "announced" number in June/08 did.
There is additional info on the international participants (at that point in time) in this link:
http://www.neura.net/channels/1.asp?id=942
Chemar has asked that we don’t argue about this any more, and I will respect that. If you wish to debate your understanding of the numbers vs. what I have just provided . . . we can talk about this further by PM (or email, if you don’t have PM rights yet), I am happy to do that. Perhaps we can come to an agreement that way, then report back here ...?
Cherie
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I am not a Neurologist, Physician, Nurse, or Hairdresser ... but I have learned that it is not such a great idea to give oneself a haircut after three margaritas
.