Ok, I have been on the methotrexate for a while and the PN has calmed a bit.. I can actually sleep now (YAY!!) and when they retested my blood my CRP level went from 34 to 18.6 and my ESR went from 46 to 34! It must be doing something! I just wish it would do more, faster... I have to go back to school soon, and I don't know who I will be able to deal with all of this.