Hi Chris,

Since you think you understand your tables better . . . let's work with them then:

I have pulled out the numbers that are relevant for the purposes of this discussion (pg 14):http://library.corporate-ir.net/libr...s%20Slides.pdf



Do you see where Table 1 and Table 2 have differing cumulative/total patient numbers; Feb (7,500 vs. 18,000), May (12,000 vs. 21,000), Sept (17,000 vs. 26,200) and Dec (21,100 vs. 30,900)?

What would YOU propose the difference in numbers between these two tables (for the same months) represent?

The difference is that the first table shows the number of patients who were on Tysabri as @ Dec/07 (including clinical trials going at that time).

The second table shows the number of patients who’ve ever been exposed to Tysabri as @ Dec/07 (including ALL clinical trials, since the beginning of time).

Do you notice that Table 2 (the one that shows the 30,900 vs. 21,900) is where the "6300 @ 12+ months" number appears?

The reason the 6300 appears in Table 2 is because the number relates to “ever been exposed”, not “on Tysabri”), just like the 30,900 number does (see Dec/07):



You said you didn’t buy that argument because in Table 2, “The safety information lists 0 (zero) patients at 1 year of therapy until Dec 2007” and “There were zero patients at one year of Therapy on the slide until the Dec 07 numbers. This couldn't possibly be true if the original clinical trials exposure were included in the numbers. They did start new trials at the same time as the recommercialization.”

Table 2 does NOT have ZERO’s (through to Dec/07), it has “dashes”. Note the titles directly above (those columns with dashes). The titles indicate the name of the various meetings that were attended (ANN, ENS, etc.) during those particular months.

What those dashes simply mean is that there was NO DATA SUPPLIED during that function/meeting, NOT that the number was zero.

*As far as the the number of “new” trial patients (since the reintroduction), it is written above Table 1 (the “on Tysabri” table), where it says: “Clinical Trials: ~700 patients on therapy in clinical trials.”

Once you understand the information from the tables you’ve supplied, I suspect the numbers supplied in my link won’t look nearly so muddy to you either. If you still don’t get it though, all I can do is hope that anyone else that cares enough about the real stats will take the time to figure it out for themselves.

Cherie