I agree too I am on Lyrica just went up to 75mg 3x daily, it does help, I feel a little "happy" but a good happy and I am also on Amitriptylene 10mg 2x nightly to help me sleep, but it does have weight gain possiable with it too so I was wondering the same thing, maybe the both together are hurting us that have gained weight (30lbs) for me ? sigh sigh sigh