Thanks for the info! I'm going to have to go in every week for a few months just to make sure - hate the blood work, but am finally getting used to it!
Why do you think the cellcept isn't working? How much pred are you on? Any other meds?
The hospital did tons of blood work b/4 they started me on the Imuran so I hope all goes well! Only time will tell!
How are you doing? Are you feeling better?
hugs!
Erin
Quote:
Originally Posted by Gabe
Some people can't metabolize Imuran and it builds up in your liver. there is a fairly easy blood test they can run before a person starts the medication that can determine if you have a genetic mutation to the enzyme thiopurine
S-methyltransferase (TPMT) that metabolizes thiopurines. If you have poor metabolism, the Imuran builds up and becomes toxic and can be very serious. There is a simple blood test that determines if you have the defective gene. They should do the blood test before starting the medication...in my case they didn't. I'm off the Imuran and started CellCept a year and a half ago. i don't think it is working
Here is a link that might explain the TPMT enzyme better.
http://www.specialtylabs.com/educati...DF/TN_1196.pdf |