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Old 01-21-2009, 11:36 AM
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mrsD mrsD is offline
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Join Date: Aug 2006
Location: Great Lakes
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15 yr Member
mrsD mrsD is offline
Wisest Elder Ever
mrsD's Avatar
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Lightbulb this restlessness

may be agitation... This side effect is reported by about 20% of patients. Its actions are too complex to predict what supplements would be helpful, at this time.

Atypical antipsychotics work on several neurotransmitters and are complex.
Quote:
SEROQUEL is an antagonist at multiple neurotransmitter receptors in the brain: serotonin 5HT1A and 5HT2 (IC50s=717 & 148nM respectively), dopamine D1 and D2 (IC50s=1268 & 329nM respectively), histamine H1 (IC50=30nM), and adrenergic α1 and α2 receptors (IC50s=94 & 271nM, respectively). SEROQUEL has no appreciable affinity at cholinergic muscarinic and benzodiazepine receptors (IC50s > 5000 nM).
from http://www.rxlist.com/seroquel-drug.htm
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