Madelyn, your husband is the first I've heard about with symptom relief from CoQ10. Not that there aren't many others, I've just not paid much attention because [and please correct me if I'm mistaken - this really confuses and bothers me] the research on CoQq10 is for
early stage pd; DXed but not yet on meds.
I found this:
http://clinicaltrials.gov/ct2/result...=&lup_s=&lup_e=
There I saw one trial for midstage pwp here:
http://clinicaltrials.gov/ct2/show/N...disease&rank=3
and the results here and typed below:
http://www.ncbi.nlm.nih.gov/pubmed/1...?dopt=Abstract
CONCLUSIONS: Nanoparticular CoQ(10) at a dosage of 300 mg/d is safe and well tolerated and leads to plasma levels similar to 1200 mg/d of standard formulations. Add-on CoQ(10) does not display symptomatic effects in midstage Parkinson disease.
I realize that neuroprotection doesn't become apparent overnight. The midstage trial was 3 months long...?
correcting this...trial dates indicate a two year span..not sure where i saw 3 months. .
oops I was correct it's in the first sentence:
"The treatment phase includes three months period of 300 mg Coenzyme Q10 per day or placebo"
And yet, I went to a health food store at the request of my husband and they sold us CoQ10 even tho I am twenty years into this disease. New research they said and they made an appointment for me to talk with someone who knew more about PD. I told my husband chances were excellent this person didn't know more than me, but I went. We had my grandson with us - 5 yrs old - they made us wait and wait while he chatted here and there, finally engaging in a long conversation with someone. My husband, beginning to believe me about knowing more agreed to return the unopened CoQ10, and we left.
The clerk came out and asked why we were leaving - I said problems with my meds. And that was that.
To my knowledge, there is no justification for anyone to be taking CoQ10 beyond early stage pd at this time.
Six years between phase II and phase III. If I am missing something - would someone please correct this information? I don't like being correct about these things anymore.
Have to expand my signature line even more to include:
what is real?
paula
