I've actually been on the Zanaflex for over a year for my TMJ. No, it doesn't seem to help much, but it DOESN'T make me sleepy (the Lyrica does enough of that). Hmmmmm.....I've never heard that Flexeril shouldn't be taken long term. My doc KNOWS I'm on it. I think a phonecall to him is warranted. It doesn't seem to help with the twitching either (I just imagine how terrible it would be without ANYTHING)......I will mention the Baclofen as an alternative. I'm thinking of going off the Lyrica because it makes me SO tired I can't stay awake (and I get REALLY low blood pressure for hours in the morning). I only take it in the evening (50mg), and I'm drugged for a good 16 hours after. I can't do that with a five year old to take care of. Thanks for responding!!!