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Originally Posted by mrsD
I don't understand this question.
Cyano B12 is not biologically active....it is converted to methyl B12 in your body if all is working as it should.(there are 4 steps that your body has to do to get to the active methyl, and some people have genetic failures along the way)
There will be NO going BACK only forward. Just make sure you take enough oral methyl B12 and on an empty stomach.
Melody chooses to remain on 5mg a day. Some people once they are healing and doing well, can reduce to 1mg a day.
Not all that you take orally is absorbed. You need high doses to get the few micrograms passively absorbed in the small intestine without intrinsic factor.
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I'll rephrase the question. Has anyone out there been suffering B12 deficiency, put on injections of cyanocobalamin. Been on these injections for a few years. Been helped by them and then changed to MethylB12 injections or sublinguals. Did you have any set backs or reactions?