do endorphins fall into the same tenor/catagory as adreniline? sorry about spelling. I would think that since hormones are linked in there with the feel good stuff that a woman's menstral cycle would call for an increase in targeted medication just before a period to counteract depression. When I was still menstrating my symptoms flaired dramatically then. But back then - there hadn't been much of any studys done and young onset was baffling to doctors. Now there is a lot more about it.