Barbara,

MuSK MG is a subtype of MG that is fairly "new" on the scene. Testing has just been out in the last several years. If you test negative for ACHR antibodies (seronegative), then your doctor will often run this test. A good percentage of those seronegatives will test positive for the MuSK antibodies.

As someone mentioned, the bulbar/ocular muscles get hit particularly hard with MuSK MG, and it is much more difficult to control. The risk of respiratory problems are also higher. However, it DOES cause generalized weakness, and the aches and pains from muscle strain are just as common in MuSK patients as "regular" MG patients.

Missy (who has MuSK MG)