Prefacing it with the mantra that all meds don't work for all people, I did have some experience with Cymbalta. After taking it for a week of or, I developed double vision. Not the cute kind, the "I literally have a 50% chance of touching the right thing" kind. I also didn't get any relief, but that may have more to do with my short time on it. I've never been on Ami, but it is a very well-tested and tried treatment for chronic pain of all kinds and likely will help you with sleep as well as Seroquel. Ami is a tricyclic antidepressant by class, so you will want to read up on the interactions and the importance of not taking too much (accidental overdoses are a fatal thing.) That said, Ami has been used for migraine pain, nerve pain, fibromyalgia pain, you name it and has proven to be pretty effective. Make friends with your Pharmacist and he will likely give you a good print out on what OTC drugs and things to avoid when taking tricyclics.
Remember, though it's easier said than done, stress increases our symptoms. View the med changes as a positive step towards controlling your symptoms. It's hell to feel like your body is on a roller coaster that your brain didn't choose to ride.
Best of luck,
Lori Lee