First- thank you, Debi for responding.

To my understanding - the FDA allows sham surgery but it doesn't have an official policy where it recommends the procedure for trials.

Since DBS surgery went through trials without using sham surgery, i still don't understand why current gene therapy trials insist upon sham surgery.

Even though I am an outspoken advocate in support of clinical trials, and I have already participated in 4 trials, I will not join a trial where sham surgery is part of the protocol.