I have tried botox shots in my palate. It is very painful and was not helpful. I suggest accupuncture and biofeedback NOT botox. Never give up because as we all know the doctors WILL give up on your case. I had one doctor prescribe me 7 months worth of Neurontin and told me "don't make another apt- don't come back - there is nothing I can do- you have no cure just take this medicine." I foolishly did - for 7 months- I took Neurontin with NO doctors care. I have been told countless times there is "no cure" and "no cause" and "no one else has this so there is nothing really on these conditions" etc. The prob is they do not research- if they did they would see this site and realize OTHER people DO have this condition! I have both spinal myoclonus and palatal myoclonus. Though I have never met anyone with spinal myoclonus. These have been devasting conditions, but I have not allowed them to devaste me - though at the beginning I totally did, but this has been going on for 6 years (p.m.) and 2 years (s.m.). The spinal myoclonus has been truly challenging because the outward spasms have been very obvious to other people. No one can tell my ears pops MANY times (5 to 61 pops) per minute. I hope you all will also remain strong. You MUST be your strongest advocate everyday and don't rely on the doctors or anyone else- rely on yourself and share with others. Best of luck. Keep in touch and keep me posted. Topsie