Hi--I was put on several antibiotics for about 6 months: Biaxin, Nasal Amikacin, and one other. Within a month I had a new lease on life and felt much better. I've had only one sinus infection since last January, when this diagnosis was made. I have, however, had aphthous ulcers of the throat, which is thought to be due to chronic infection or immunosuppression.

This lead to an immuno w/u and more culturing, and I tested positive for lyme disease, as well as not making immune antibodies of the IgG sort.

So now I am on antibiotics again, which the doctors I am seeing concurring that I have chronic lyme, that the mycobacterium was probably innocent, that many people carry it, and that the reason I felt better was that my lyme was being treated.

Go figger. They say I'm in for another year of antibiotics, and are pushing for IV. I've been pushing back, wanting a bit of a normal life, but I'm pretty sure I'll give in in a month or so. I do not feel anything like the way I did the first few months on antibiotics last year, and it's typical of lyme that antibiotics need to be rotated, because the bacteria changes forms.

I hope treatment helps you, but if it's just sinuses, it may not be the culprit.
My sinus guy who treated it is rare, with most of the other ENT/sinus guys thinking that many people harbor these organisms harmlessly. I don't know, myself.

Good luck.