RESPONSE TO paulmethyl

Paul,

MY SUCCESS:
After taking 1000 mg a day of cynacobalamin (sublingual Superior Source) for three months, my B12 increased markedly. After over three years, I personally have had no rashes or skin problem. (Note: I’m also allergic to penicillin.) Could any of the other medications you were taking be the cause of the cyst reaction?) See history and details below:

I’m a sufferer of B12 deficiency. I originally took injections and had a severe rash reaction on my face, arms and legs. They were not cyst.

I was told it was probably the liver extract that was added to the injection. I didn’t have the reaction when the liver extract was omitted. Recently I’ve read that the serum used to deliver B12 causes rash reactions

At one point In my life, my anemia was constantly below the transfusion point with no know explanation as to why. When it reached an alarming low below the transfusion point, I was hospitalized immediately. A bone marrow aspiration revealed megaloblast. I was given injections of iron weekly (max dose), 12 folic acid pills a day (max dose available), prescription multivitamins, and B12 injections weekly. Finally, after 63 iron and 63 B12 shots, my hemoglobin raised to at or just belos the transfusion of both the commonly used blood test.

I borrowered a nurse friend’s nutrition book. I researched sources of B12 and iron. It appears that while plants have a form of B12 in them, we can’t absorb them. The maximum natural B12 source is animal meats with red meats being the best and the internal organs (liver) the highest source. I didn’t like liver, finally learning to like chicken livers first and now beef and pork livers. My doctor said that cynacobalamin is the absorbable source of B12 that we get from food. And, for ten years I ate mega overdoes of these foods, including the vitamin supplements. I purchased hind quarters of beef and ate it with fruits (dried and fresh), nuts, and veggies. I was determined to beat this. After almost ten years on this diet the anemia gave way to a maintained very low normal reading.

What I didn’t know and I understand was not common knowledge at the time, was that having the anemia in the “normal” range, which large doses of folate can do, does not mean the megaloblastic condition is gone. One of the diagnostic testing tools used to test anemia may appear normal, as mine was low normal; but the insidious megaloblastic anemia, a form of pernicious anemia, is still present.

I continued to have all types of symptoms – that I understand now are symptoms for problems that include B12 deficiency. The amount of red meat, including chicken and beef livers made my low readings questionable. I progressively got worse until my neurologist notice my history of anemia and questioned me about it. The bone marrow aspiration revealing megaloblast resulted in him placing me on B12 therapy again – for the rest of my life he said. We first tired the B12, B6, Folate combination in the sublingual form by Superior Source, checking my B12 levels three months later.

During this three months time I researched everything credible I could find to determine the side affects of B12. I’m very cautious about taking any kind of medication; so the idea of taking anything for the rest of my life demanded I knew what the possible side effects could be. The only thing I found was reactions to the serum that is used in injections to deliver the B12. Since my appointment with my internist was before the neurologist, I asked him what the side effects of cynacobalamine are – sharing that I only found reactions to the serum used to deliver the B12. He said, Do you know why you couldn’t find it? I said, “No.” He said it was because there are no known side effects of B12. He said research had been done utilizing extremely high doses with no known side effects.

After my mother’s death we (six siblings) had an autopsy on her brain done. The pathologist said the brain did not reveal the usual Alzheimer pathology. He said there were tiny spots of dead cells throughout her brain. When I queried my neurologist as to what could have caused mother’s condition (previously diagnosed as Alzheimer), he said B12 deficiency, tiny strokes, or a vascular condition.

If you were taking other medications, they or a combination thereof, may also be the cause of the cyst. But, there is the possibility that the serum in the methycobalamin may be the problem. Have you tried sublinqual B12 – cynacobalamin and/or methylcobalamin?

I CURRENTLY TAKE 1000 mgs of both cynacobalamin and methycobalamin, sublingual, Superior Source, with no side affects. It is my understanding that the natural way (food, red meat etc) we receive B12 is cynacobalamin. The liver then converts a small portion into methycobalamin, that is believed to be utilized to maintain and restore neurological functions. Therefore, in an abundance of caution, having found no know side affect to B12 in and of itself, I take both.
PLEASE, if you haven’t already, CHECK OUT THE SERUM. If you have found research that disputes my findings, please share.
LANEE

OTHER INFORMATION MAY BE FOUND AT THIS SITE:

More common causes of pernicious anemia include:
• Weakened stomach lining (atrophic gastric mucosa)
• The body's immune system attacking the cells that make intrinsic factor (autoimmunity against gastric parietal cells)
• Autoimmunity against intrinsic factor itself
The disease begins slowly and may take decades to fully establish. Although the congenital form occurs in children, pernicious anemia usually does not appear before age 30 in adults. The average age at diagnosis is 60.
Risk factors include:
• Family history of the disease
• History of autoimmune endocrine disorders, including:
o Addison's disease
o Chronic thyroiditis
o Graves disease
o Hypoparathyroidism
o Hypopituitarism
o Myasthenia gravis
o Secondary amenorrhea
o Type 1 diabetes
o Testicular dysfunction
o Vitiligo
• Scandinavian or Northern European descent
In addition to pernicious anemia, other causes of vitamin B12 deficiency include:
• Certain drugs, including colchicine, neomycin, and para amino salicylic acid (used for tuberculosis treatment)
• Gastrointestinal disease (stomach removal surgery, celiac disease, Crohn's disease)
• Infection (intestinal parasites, too much growth of bacteria in the small intestine)
• Metabolic disorders (methylmalonic aciduria, homocystinuria)
• Nutritional problems (strict vegetarians who do not get vitamin B12 supplementation, poor diet in infancy, or poor nutrition during pregnancy)