I am just so sorry to hear this, Bren.

I am sitting here puzzling over this, trying to figure out all the angles, as I am sure you are also.

Only you can make the decision as to whether to try to continue for a few more months. You have to go through all the evidence- the MRI, the way you FEEL, whether your symptoms are returning, whether you have any adverse reactions when you have your infusions, etc.

You also have to decide whether you trust that your neuro is looking out for you and has your best interests at heart.

It's true that the antibodies may be transient, even now, but you have to add it all up and decide.

I also did Copaxone before Tysabri. It didn't work for me but that does not mean it won't for you. There are other drugs in the works now too.

I understand about your husband's concerns. I had to finally tell my fiance that I had done my homework and that I was going to do what I thought was the very best for me, and that even that was no guarantee that at some point I would prevent disability, since in essence, even with treatment, so far, people with MS progress. He didn't want to hear it, but hear it he did.

It's a lot easier now, because he partners with me to keep me healthy rather than fighting me when he doesn't understand. My neuro and I explain everything to him in easy to understand terms and keep answering his questions until he is satisfied.

Take some time and just think it all over. You'll find an answer in your heart and your mind and in the end, it is your decision as to where you go from here.

Let us know how you are. WE care and we are here for you if you need to talk.