http://jcn.sagepub.com/cgi/content/abstract/24/2/170
Journal of Child Neurology, Vol. 24, No. 2, 170-175 (2009)
DOI: 10.1177/0883073808322666
Tourette Syndrome and Comorbid Pervasive Developmental Disorders
Larry Burd, Qing Li, Jacob Kerbeshian, Marilyn G. Klug, Roger D. Freeman
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We found 334 (4.6%; 1 of every 22 participants) with Tourette syndrome had a comorbid pervasive developmental disorder.
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Variables from logistic modeling that were significant predictors of Tourette syndrome and pervasive developmental disorders were: male gender; no family history of tics/Tourette syndrome; and an increased number of comorbidities (P < .001).
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We found rates of comorbid Tourette syndrome and pervasive developmental disorders to be increased by 13 times. Identification of differences between subgroups of patients with Tourette syndrome may increase understanding of syndromal susceptibility, severity, and outcome.
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Note: this study involved the Tourette Syndrome International Database Consortium Registry.