Cheryl, Jim did. He was on Beta way back in the day. Tried Copax and then Avonex. Now back to Beta and doing fine on it. The only place he has site reactions is when I do it in his stomach. The needles are much smaller now too so that should help. We haven't opened the smaller needles yet because the VA took their time getting the new ones. Waste not I guess. lol

No symptoms for Jim whatsoever. He does seem to have some stiffness the day after but we're not convinced just yet it's the Beta. Other than that, nothing. No more staying in for days like with Avonex. I do pre medicate with Ibuprofen. I tried Tylenol once and he ran a fever so I would recommend Ibuprofen or something similar.

Good luck!