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In Remembrance
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Join Date: Aug 2006
Posts: 3,772
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In Remembrance
Join Date: Aug 2006
Posts: 3,772
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it's not really about depression
This is something I have been up to my neck in the last few months and is very complex, so please forgive the shortcuts here.
One of the primary factors, if not THE primary factor, in PD is the exposure of fetus or child to bacterial toxins called LPS during critical windows of development of the neurological and endocrine systems.
This has several lingering effects. One of the critical ones is an imbalance in the relationship between the hypothalamus, pituitary, and adrenal glands (HPA).
This imbalance results in, among other things, chronic elevation of cortisol levels - a chronic stress reaction.
Restoring HPA balance can have major effects in PWP.
Antidepressants are one way to try to do that. But there is a real question as to whether they are the best way. There are many side effects to watch for.
If you are not truly depressed you might look into other stress lowering techniques instead.
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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