Originally Posted by KAOheim

Another down side of the copaxone is the daily factor and the size. Those shots are freakin HUGE. More than 4 times as much liquid, 100mcl vs. 22mcl. And it's the manitol that makes the difference not the med. Course you need both.

The rebif 22's are nice and small, as am I, and so far so good mostly. If I have trouble I may think about upping the dose again. I find naproxen to be the best premed because it lasts for such a long time. Since rebif is hard on your liver I try to avoid tylenol like the plauge. Course the naproxen and ibuprofen are hard on your kidneys. But I like my liver more than my kidneys anyolewhoo.