I've read some MSers get "tight stocking Syndrome." When I taught many autistic kids could not stand the rubbing of clothes labels and parents were always cutting those out. MSers get "over-stim-ed" too IMHO. I never wear pants (unless I know company's coming) but I feel like I always feel like I have thin cotton pajama bottoms on. My jeans feel lousy also because I've gained not weight, but everything shifted. I'm cold, I'm hot. Like Goldilocks nothing is ever just right.