I take sinemet and requip. 600 mg and 24 mg respectively. Lately I have been experimenting and find that requip greatly increases my own dyskinesia but that the sinemet is much smoother. Sinemet doses of 1200 mg are not unusual, so you have a high ceiling. And there is the age issue - at 59 I have to "pace" myself differently than you do at 78. Every new drug brings its own problems, too. Finally, Ldopa causes a certain amount of damage itself so I take alpha lipoic acid and acetyl-L-carnitine to counter some of that. Good luck.
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Originally Posted by accu2001
Most PD patients start with an agonist and as their pd progresses add Levodopa.I was diagnosed 7 years ago at the age of 71 and started medicating with Levodopa.I am taking 300mg daily.Recently my symptoms have progressed,especially my rigidity.As the Levodopa causes a mild case of Dyskinesa,I prefer not to increase the Levodopa.From your experience ,would adding a agonist decrease ther rigidity?
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