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Old 04-10-2009, 10:56 AM
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mrsD mrsD is offline
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mrsD mrsD is offline
Wisest Elder Ever
mrsD's Avatar
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Lightbulb

Here is a blog entry in plainer English (which I myself needed to fully grasp the seriousness of this new paper.)

http://bloodbrainbarrierblog.blogspo...elination.html

Quote:
This not only suggests that relapsing/remitting MS patients should be carefully monitored while taking simvastatin (if they should be taking it at all in the first place), but that long-term treatment with simvastatin could have profound effects on the CNS. This should definitely temper the enthusiasm expressed by the American Academy of Pediatrics last year for giving statins to children as young as eight years old.
Simvastatin was used because it is more fat soluble and hence gets into the brain in higher amounts than some of the other statins.
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