Yes. Clinically Isolated Syndrome looks like MS, has a defective neuro exam and positive findings on MRI but it is a first episode and none other has been able to be previously identified. I don't know the stats but they are high that those with CIS who are treated with an interferon have a far better chance after 5-10 years of not having another episode and not becoming Clinically Definite MS than those who are not treated. Most of those ultimately end up with a diagnosis of clinically definite MS.


Mark Freedman recently wrote an article or was interviewed in an article from the ECTRIMS conference and addressed this finding. If you search www.medscape.com and ECTRIMS you should find the article which is entitled (I think) An Interview with Dr. Mark Freedman: Highlights of ECTRIMS. May not be that exact title but it'll be close.