My rsd when it does a large attack it makes my pain sky rocket outta control beyond the extreme it is now, in which my body can't take it so it revolts against the pain even though it can't do anything to stop it and only makes things worse for itself. When my body revolts it becomes extremely itchy all over or at other times in just certian places, because of the pain levels i begin puking and as well my body becomes so weak i get dizzy/light headed and daze in and out of being alert and falling asleep. Your body temp can have you feel like your boiling or freezing or some parts of each. Its all the joy of attacks. I've Seen Small, Medium, Large & Extreme ones and even the smallest are very hard to deal with. So with the question of can RSD cause itching yes it can very much so. Itching so bad your literally scratching ur skin off. Or anything in between. Hope it settles down for you.