LizaJane,

I can't think of many medicines without some fatal risk. The new January Discover Magazine has a chilling article in "Vital Signs" about a poor woman who died from pseudomembranous colitis caused by a short course of the antibiotic Clindamycin. The article points out that many antibiotics including the penicillins carry this risk, as does acid reducing medication (I take Aciphex daily).

The author is Dr. Tony Dajer, Interim Chief of ER Medicine at New York Downtown Hospital.

I have questions about your Methotrexate concerns. Is the bone marrow supression asymptomatic? Can it be detected through testing before it progresses to dangerous levels? If so, is that testing normal procedure? Is the bone marrow supression reversable if caught early and the Methotrexate stopped?