Quote:
Originally Posted by lady_express_44
EACH of the PML cases has it’s own individual “story”, and I'm really not interested in re-hashing each case with you again.
I think it suffices to say that some were on Avonex, some had/were treated with steroids, and yet others were only ever previously on DMD’s or NOTHING before starting Tysabri. Some come from America, others are from the UK. Some lived & some died. All very sad.
All 9 got PML, and they wouldn’t have gotten it without Tysabri.
Fully informed means understanding the risks . . . at least it does in my opinion. 
This information is NOT posted for the benefit of those who've already decided 1:1000 is a comfortable risk ratio. It is an update for those who HAVEN'T yet decided.
Cherie |
What's sad is what MS does to people physically and mentally and the corresponding impacts on family and friends.
Sorry, but the PML cases do have to be looked at at least in groups - PML risk and outcomes in the trial where they were using other immunnosuppressants/weren't looking for it/treating it and PML risk and outcomes in commercial use where they are using it in monotherapy/they're looking for PML and trying to treat it.
As I've said before risk is a function of chances of occurring and outcome of occurrence. If your concern is to fully inform patients considering Tysabri please give them the full and accurate information.