My wife received a one day 4 hour infusion of lidocaine several months ago with no benefit. She seemed to have taken the infusion well considering having RSD for 7 years as far as side effects. She and I think that she didn't receive relief from the lidocaine, and earlier ketamine infusions and shots, is because of the length of time she's had RSD. She does, however, like lidocaine cream that she applies on her sore areas, temporary as it is.