Hmm, yes, if you google it, the potential side-effects of lenalidomide are as long as your arm, and much more scary. Very scary. And, on top of that, as a chemical relative of thalidomide, it also has the same risks to an unborn foetus.

So it strikes me that this is a drug with very specific potential benefits e.g. for bone cancer, but not one to be used off-label *at all*. On the other hand, full body or very severe RSD might fall into the on-label use, I suppose that's why they're doing the trial.

I'm far too much of a coward to be tempted to try it, even if I was more affected by RSD than I am - so far I've been very lucky and the RSD has confined itself to my left wrist and hand - might be a different story otherwise, though.....
all the best