I took mine four hours apart when first diagnosed - now I take 60 mg every 3 hours - like clockwork. I take one about 20 mins before I get out of bed in the morning and then every 3 hours. Thankfully I don't get an upset tummy from them so I don't need to worry about taking them with food. My best suggestion to you (other than speaking to your doctor) is to listen to your body. I could always feel my eye starting to droop or my arms starting to feel heavy.

Good luck!
~Kathy