I take mine at 9 am, 4 pm and 11 pm. When I forget the 4 pm, I feel it at about 6 pm…
I therefore think that Mestinon should be taken when needed, try different schedules and keep the one which fits you best. It could also vary according to your activities…
When I was on a 5 x 60 mg Mestinon schedule, I took also Timespan Mestinon during the day, although it is much more expensive, it can also be easily broken in two (i.e. 90 mg) and I appreciated that convenience when I needed to stay without medication for about 5 hrs during the afternoon (bridge tournaments, for instance…)
Maurice.