I don't know anything scientific, however before I ever knew what was wrong with me a few years ago I was undergoing a VERY stressful time both at work and at home in the worst ways. It caused me to get so sick that I could hardly function. After being off work three months in the summer I still could not function and had to let the school know that I was taking a year off. I couldn't function enough to try to get disability, we just lived mostly off my savings. I spent most of the year in bed just trying to function when I needed as a mom.

Then when I went back to work I would get to wear when I had deadlines and other stressful situations I just couldn't hardly function.

Well now I know what was going on. And I truly know in the bottom of my heart that stress does cause ms relapses to be very bad.

So for what this is worth, which is just my opinion, to answer your question, yes I believe stress can cause exaserbations to be worse!!!