Quote:
Originally Posted by jackD
This study and the conclusions are a JOKE!!
I need a few more glasses of wine and a little food before I expand my comments.
Read it with a critical eye and see if you can see some possible flaws/weaknesses in it.
jackD
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In addition to some of the weaknesses noted by others I strongly object to the fact that the study(joke) only included 15 MS folks!!!
Even calling this small study a "pilot" study would be weak.
Some responder/nonresponder categories were 2 or 3 people!!!
Also the Interferon Beta used was Interferon Beta 1b.
This in an inferior version of the Human interferon Beta 1a which is usad in Avonex and Rebiff which is nearly identical to the Human interferon Beta. The Beta 1a designation is only used to identify that it was artifically constructed.
Interferon Beta 1b therefore has a higher rate of devoloping neutralizing antibodies. However they make conclustion about ALL interferon Beta treatment. Avonex a true version of Human Interferon Beta produces much less antibody formation partly because it is injected way under the highly reactive skin and partly because it is almost exactely the same as the Interferon Beta or own bodies produce. Much of our reaction to these drugs comes from other plasma material stuff in the liquid mix injected.
jackD