Hi Desinie,

I've been diagnosed with MS for over 30 years now, and I'm sure you're aware that IV MethylPred wasn't thought of way back then. Even the ABC drugs weren't invented until the late 70's or early 80's, so all of my early exacerbations were treated with oral Prednisolone, and I always got better.

So, oral does work.

I did get more side effects with the oral form than I got with the IV version (having had both), but I personally think that has something to do with the time that some-one is on the medication.

IV Methylpred is over in 3-5 days, where oral is administered in a tapering dose....usually over 3-4 weeks.

I always blew up more with the moon face and the flluid retention on oral than I did on IV. In fact, for me the only side effect on IV was the horrid taste in my mouth, and a racing heart..... but others have more side effects than I did.