but quinolones have NOT been around for 30 years, in the USA.

Cipro was the first here. It's patent expired in 2003. That makes it 13 or 14 yrs old thereabouts.

It is also not accurate to use the -myacin suffix as safe. There a many
mycins that are NOT related to each other, and some which are very toxic.

Gentamycin, and tobramycin are neurotoxic to some people.
Streptomycin is rarely used and also quite hazardous. These are called aminoglycosides.

Achromycin, Terramycin, Vibramycin are in the tetracyline family. (not toxic)

Adriamycin is a chemo agent and can damage the heart.

Erythromycin and Azithromycin (Zithromax) and clarithromycin (Biaxin) are in the family of macrolides.

Clindamycin is very hard on the GI tract, but is useful for deep tissue infections and bone infections(anaerobic). It can cause severe colitis in some people. It is called a lincosaminde.

We have had many posters in the past, who claimed damage from fluroquinolones. This family of drugs, is very problematic for some people.
It also causes tendon ruptures for some. Not everyone reacts to the neuro potential of the quinolones. Cipro in short course treatments is usually well
tolerated. Long term however, increases risk.
Some quinolones have been recalled/discontinued. Omniflox was one.
Some have fallen into disuse because of CNS side effects/seizures= Floxin

Some on this board have had this experience with fluroquinolones. There is a book written about them called Bitter Pills, by Stephen Fried.